2 Sep 2016

Disarming the most dangerous of superbugs

Zebrafish embryos show a 'hot spot' of neutrophils happening when
the specific bacterial metabolic pathway is blocked. Those neutrophils
then eliminate the bacteria very quickly.  Image:
www.pnas.org/content/early/2016/08/08/1523116113
Among the six most deadly antibiotic-resistant bacteria in the world, Acinetobacter baumannii targets the sick and elderly in hospitals. Now, researchers from Monash University have uncovered a way to effectively turn the patient’s immune system into an assassin against this lethal invader.

Led by Professor Anton Peleg, head of the Department of Infectious Diseases in Monash’s Central Clinical School and lab leader in the Biomedicine Discovery Institute, the research team developed a zebrafish model which allows scientists to study real-time interactions between immune cells and the deadly bacteria A. baumannii during infection.

26 Aug 2016

Photo of the week: Trauma care at the Alfred

Professor Mark Fitzgerald and a team of trauma medical staff talking with a patient during ward rounds.
Prof Mark Fitzgerald is Director of both the Alfred Trauma Service and the National Trauma Research Centre. Mark will be giving CCS's public lecture on 12 October on innovative systems of trauma care. The Victorian State Trauma System has halved the odds of dying after serious injury since its inception in 2001! [Ref] All welcome. See more:

Forthcoming CCS events 29 Aug - 2 Sep 2016: Seminars, public events, general notices

Pin Shie Quah
Central Clinical School has regular seminar series and postgraduate presentations. All event notices are maintained on the CCS Events calendar.

CCS staff & students can see details of both public and local events (including professional development courses, trade fairs and Graduate Research Student calendars) and deadlines, at the Intranet's Announcements page.Various departments have their own calendars. See CCS seminar index: www.med.monash.edu.au/cecs/events/seminars.html

What's on for next week 29 Aug - 2 Sep 2016:

Wed 31/08/2016 11:30 PhD pre-submission seminar : Ms Pin Shie Quah
Thu 01/09/2016 11:30 PhD Confirmation Seminar : Mr Xianwei Che

01/09/2016 12:00

Forthcoming events

http://med.monash.edu.au/cecs/events/2016-public-lecture-fitzgerald.html

Short course: 25-28 Oct 2016 Introduction to Clinical Trials

Introduction to Clinical Trials short course in progress at CCS
Central Clinical School's Introduction to Clinical Trials short course will consist of formal lectures, small group discussions and workshops. The course aims to develop fundamental knowledge in clinical trial study design and co-ordination.

It will provide specific instruction in developing a clinical research question and creating a concise protocol that includes literature review, study design, subject sampling and recruitment, instruments and other measurement approaches, sample size, consent form, budget and timetable.

Recent CCS publications: Week ending 26 Aug 2016

L-R: Adj A/Prof Elizabeth Gardiner and
A/Prof Robert Andrews
Recent publications (10) for Central Clinical School affiliated authors in the departments of ACBD, Immunology, Infectious Diseases, MAPrc, MSHC, Neurosciences:

Australian Centre for Blood Diseases

Berndt MC, Andrews RK. Liver-mediated shedding of platelet GPVI. Blood. 2016 Aug 11;128(6):751-2. doi: 10.1182/blood-2016-07-723973.

Program transforms pre-surgery weight loss care

by Anne Crawford

An educational program developed by Monash University and Alfred Hospital researchers to better prepare patients for bariatric (weight loss) surgery is revolutionising their care, streamlining its delivery and leading to improved weight loss after surgery.

The program was based on a study overseen by Professor Wendy Brown, director of the Centre for Obesity Research and Education (CORE), and Associate Professor Peter Nottle, director of Upper Gastrointestinal Surgery at the Alfred Hospital.

Congratulations to Gastroenterology for NHMRC '10 of the best' 2015

The National Health and Medical Research Council has announced its pick for 2015 research in its "Ten of the Best".
Congratulations to Peter Gibson and his team for their research on the actual effect of gluten in IBS being chosen as one of the ten. The document quotes Prof Gibson as saying:
“We demonstrated that gluten, without FODMAPs, did not specifically induce symptoms in patients who believed they were gluten intolerant.
“Indeed, all patients experienced reduced gut symptoms in the run-in period when they, for the first time, restricted all FODMAPs in their diet.
“We found no changes in the physiology of the gut in response to gluten.”
Link: 
https://www.nhmrc.gov.au/_files_nhmrc/file/publications/nhmrc_-10-of-the-best-2015_0.pdf
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